Spine density on neostriatal neurones changes with 6-hydroxydopamine lesions and with age

@article{Ingham1989SpineDO,
  title={Spine density on neostriatal neurones changes with 6-hydroxydopamine lesions and with age},
  author={Cali A. Ingham and S. H. Hood and Gordon William Arbuthnott},
  journal={Brain Research},
  year={1989},
  volume={503},
  pages={334-338}
}
  • Cali A. Ingham, S. H. Hood, Gordon William Arbuthnott
  • Published in Brain Research 1989
  • Medicine, Biology
  • Golgi-impregnated medium-size spiny neurones were studied in the rat neostriatum at various times after a unilateral 6-hydroxydopamine lesion of the medial forebrain bundle. At both short (12-26 days) and long (7-12 months) survival times, the density of spines was significantly lower (13%) on neostriatal neurones ipsilateral to the 6-hydroxydopamine injection. At longer times the density of spines was lower on neurones both ipsilateral and contralateral to the lesion when compared to neurones… CONTINUE READING

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