Spine changes associated with long-term potentiation.

@article{Muller2000SpineCA,
  title={Spine changes associated with long-term potentiation.},
  author={Dominique Muller and Nicolas Toni and P A Buchs},
  journal={Hippocampus},
  year={2000},
  volume={10 5},
  pages={596-604}
}
High-frequency stimulation of excitatory synapses in many regions of the brain triggers a lasting increase in the efficacy of synaptic transmission referred to as long-term potentiation (LTP) and believed to contribute to learning and memory. One hypothesis proposed to account for the stability and properties of this functional plasticity is a structural remodeling of spine synapses. This possibility has recently received support from several studies. It has been found that spines are highly… CONTINUE READING

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