Spindle assembly: asters part their separate ways

@article{Rosenblatt2005SpindleAA,
  title={Spindle assembly: asters part their separate ways},
  author={Jody Rosenblatt},
  journal={Nature Cell Biology},
  year={2005},
  volume={7},
  pages={219-222}
}
  • J. Rosenblatt
  • Published 1 March 2005
  • Biology, Physics
  • Nature Cell Biology
Cells have developed diverse ways to separate two microtubule asters to form a mitotic spindle. Here, I focus on two mechanisms used to position asters around chromosomes during mitosis: first, aster migration around the nuclear envelope and, second, aster attachment to a contractile cortex at the plasma membrane after the nuclear envelope has broken down. Although certain cell types use one mechanism predominantly, most rely on both to ensure proper spindle assembly. 

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