Spinal subarachnoid space pressure measurements in an in vitro spinal stenosis model: implications on syringomyelia theories.

@article{Martin2010SpinalSS,
  title={Spinal subarachnoid space pressure measurements in an in vitro spinal stenosis model: implications on syringomyelia theories.},
  author={Bryn A. Martin and Richard Labuda and Thomas J. Royston and John N. Oshinski and Bermans J. Iskandar and Francis Loth},
  journal={Journal of biomechanical engineering},
  year={2010},
  volume={132 11},
  pages={
          111007
        }
}
Full explanation for the pathogenesis of syringomyelia (SM), a neuropathology characterized by the formation of a cystic cavity (syrinx) in the spinal cord (SC), has not yet been provided. It has been hypothesized that abnormal cerebrospinal fluid (CSF) pressure, caused by subarachnoid space (SAS) flow blockage (stenosis), is an underlying cause of syrinx formation and subsequent pain in the patient. However, paucity in detailed in vivo pressure data has made theoretical explanations for the… CONTINUE READING

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