Spinal implants of olfactory ensheathing cells promote axon regeneration and bladder activity after bilateral lumbosacral dorsal rhizotomy in the adult rat.

@article{Pascual2002SpinalIO,
  title={Spinal implants of olfactory ensheathing cells promote axon regeneration and bladder activity after bilateral lumbosacral dorsal rhizotomy in the adult rat.},
  author={Juan Ignacio Pascual and Graciela Gudi{\~n}o-Cabrera and Ricardo Insausti and Manuel Nieto-Sampedro},
  journal={The Journal of urology},
  year={2002},
  volume={167 3},
  pages={1522-6}
}
PURPOSE We performed spinal implantation of olfactory ensheathing cells to demonstrate dorsal root afferent regeneration as well as bladder activity restoration after lumbosacral L6 to S2 rhizotomy. MATERIALS AND METHODS Spinal segments receiving bladder innervation, usually L6, S1 and S2, were identified by bipolar stimulation of the ventral roots. Bilateral section of the identified dorsal roots L6 to S2 was performed in 18 male Wistar rats. Immediately after rhizotomy olfactory ensheathing… CONTINUE READING

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