Spinal cord stimulation improves ventricular function and reduces ventricular arrhythmias in a canine postinfarction heart failure model.

@article{Lopshire2009SpinalCS,
  title={Spinal cord stimulation improves ventricular function and reduces ventricular arrhythmias in a canine postinfarction heart failure model.},
  author={John C. Lopshire and Xiaohong Joe Zhou and Cristian Petru Duşa and Takeshi Ueyama and Joshua Rosenberger and N. J. D. Courtney and Michael R. Ujhelyi and Thomas Mullen and Mithilesh K. Das and Douglas Peter Zipes},
  journal={Circulation},
  year={2009},
  volume={120 4},
  pages={286-94}
}
BACKGROUND Spinal cord stimulation (SCS) reduces the incidence of ventricular tachyarrhythmias in experimental models. This study investigated the effects of long-term SCS on ventricular function in a postinfarction canine heart failure model. METHODS AND RESULTS In stage 1, dogs underwent implantable cardioverter-defibrillator implantation and embolization of the left anterior descending artery followed by right ventricular pacing (240 ppm) for 3 weeks to produce heart failure. In stage 2… CONTINUE READING
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