Spinal cord protection during aortic cross-clamping using retrograde venous perfusion.

@article{Parrino1999SpinalCP,
  title={Spinal cord protection during aortic cross-clamping using retrograde venous perfusion.},
  author={Patrick E Parrino and Irving L. Kron and S. D. Ross and Kim S Shockey and M. J. Fisher and John R. Gaughen and John A. Kern and Curtis G. Tribble},
  journal={The Annals of thoracic surgery},
  year={1999},
  volume={67 6},
  pages={1589-94; discussion 1594-5}
}
BACKGROUND Paraplegia remains a devastating complication following thoracic aortic operation. We hypothesized that retrograde perfusion of the spinal cord with a hypothermic, adenosine-enhanced solution would provide protection during periods of ischemia due to temporary aortic occlusion. METHODS In a rabbit model, a 45-minute period of spinal cord ischemia was produced by clamping the abdominal aorta and vena cava just below the left renal vessels and at their bifurcations. Four groups (n… CONTINUE READING

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