Spinal cord NR1 serine phosphorylation and NR2B subunit suppression following peripheral inflammation

@article{Caudle2005SpinalCN,
  title={Spinal cord NR1 serine phosphorylation and NR2B subunit suppression following peripheral inflammation},
  author={Robert M Caudle and Federico M. Perez and Arseima Y Del Valle-Pinero and Michael J Iadarola},
  journal={Molecular Pain},
  year={2005},
  volume={1},
  pages={25 - 25}
}
BACKGROUND Spinal cord N-methyl-D-aspartate (NMDA) receptors are intimately involved in the development and maintenance of central sensitization. However, the mechanisms mediating the altered function of the NMDA receptors are not well understood. In this study the role of phosphorylation of NR1 splice variants and NR2 subunits was examined following hind paw inflammation in rats. We further examined the level of expression of these proteins following the injury. RESULTS Lumbar spinal cord… CONTINUE READING
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Pharmacological characterization of the chronic constriction injury model of neuropathic pain

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