Spinal astrocytic activation contributes to mechanical allodynia in a mouse model of type 2 diabetes.

@article{Liao2011SpinalAA,
  title={Spinal astrocytic activation contributes to mechanical allodynia in a mouse model of type 2 diabetes.},
  author={Yong-Hui Liao and Gui-He Zhang and Dong Jia and Peng Wang and Niansong Qian and Fei He and Xiang-Tian Zeng and Yong He and Yan-ling Yang and Da-yong Cao and Yi Zhang and De-sheng Wang and Kai-shan Tao and Chang-jun Gao and Kefeng Dou},
  journal={Brain research},
  year={2011},
  volume={1368},
  pages={324-35}
}
Diabetic neuropathic pain (DNP) plays a major role in decreased life quality of type 2 diabetes patients, however, the molecular mechanisms underlying DNP remain unclear. Emerging research implicates the participation of spinal glial cells in some neuropathic pain models. However, it remains unknown whether spinal glial cells are activated under type 2 diabetic conditions and whether they contribute to diabetes-induced neuropathic pain. In the present study, using a db/db type 2 diabetes mouse… CONTINUE READING
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Mousemodels of diabetic neuropathy

  • K. A. Sullivan, J. M. Hayes, +5 authors E. L. Feldman
  • Neurobiol . Dis .
  • 2007
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