Spinal NK1 receptors contribute to the increased excitability of the nociceptive flexor reflex during persistent peripheral inflammation.

Abstract

Hyperalgesia is a characteristic of inflammation and is mediated, in part, by an increase in the excitability of spinal neurons. Although substance P does not appear to mediate fast synaptic events that underlie nociception in the spinal cord, it may contribute to the hyperalgesia and increased excitability of spinal neurons during inflammation induced by… (More)

Topics

Cite this paper

@article{Parsons1996SpinalNR, title={Spinal NK1 receptors contribute to the increased excitability of the nociceptive flexor reflex during persistent peripheral inflammation.}, author={A. M. Parsons and C. Honda and Y P Jia and D{\'o}ra Budai and X. J. Xu and Zsuzsanna Wiesenfeld-Hallin and Virginia S Seybold}, journal={Brain research}, year={1996}, volume={739 1-2}, pages={263-75} }