Spinal MRI in patients with suspected multiple sclerosis and negative brain MRI

@article{Thorpe1996SpinalMI,
  title={Spinal MRI in patients with suspected multiple sclerosis and negative brain MRI},
  author={JohnW. Thorpe and D R Kidd and Ivan F. Moseley and Alan J. Thompson and David G. MacManus and D. Alastair S. Compston and W. Ian McDonald and David H. Miller},
  journal={Brain : a journal of neurology},
  year={1996},
  volume={119 ( Pt 3)},
  pages={
          709-14
        }
}
Although MRI detects the white matter lesions of multiple sclerosis within the brain with high sensitivity, a minority of patients have normal brain MRI. We describe 20 patients, selected from over 170 who had undergone brain imaging with minimal (n = 12) or no (n = 8) abnormalities (median number of lesions = I, range, 0-3) but in whom spinal MRI was abnormal. Twelve had clinically definite or laboratory supported definite multiple sclerosis according to the Poser criteria; one had clinically… CONTINUE READING
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