Spina bifida

@article{Mitchell2004SpinaB,
  title={Spina bifida},
  author={Laura E Mitchell and N. Scott Adzick and Jeanne Melchionne and Patrick S Pasquariello and Leslie N Sutton and Alexander Steven Whitehead},
  journal={The Lancet},
  year={2004},
  volume={364},
  pages={1885-1895}
}
Spina bifida results from failure of fusion of the caudal neural tube, and is one of the most common malformations of human structure. The causes of this disorder are heterogeneous and include chromosome abnormalities, single gene disorders, and teratogenic exposures. However, the cause is not known in most cases. Up to 70% of spina bifida cases can be prevented by maternal, periconceptional folic acid supplementation. The mechanism underlying this protective effect is unknown, but it is likely… Expand
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References

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Spina bifida is a congenital condition of the nervous system. It typically results in paralysis of the lower limbs, hydrocephalus, incontinence of bowel and bladder, lack of sensation below theExpand
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