Spike timing-dependent selective strengthening of single climbing fibre inputs to Purkinje cells during cerebellar development

Abstract

Shaping functional neural circuits in developing brain involves activity-dependent refinement of early-formed redundant synapses. In the developing cerebellum, a one-to-one connection between a climbing fibre (CF) and a Purkinje cell (PC) is established by selective strengthening of a single CF followed by elimination of surplus CFs. Here we investigate… (More)
DOI: 10.1038/ncomms3732

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Cite this paper

@inproceedings{Kawamura2013SpikeTS, title={Spike timing-dependent selective strengthening of single climbing fibre inputs to Purkinje cells during cerebellar development}, author={Yoshinobu Kawamura and Hisako Nakayama and Kouichi Hashimoto and Kenji Sakimura and Kazuo Kitamura and Masanobu Kano}, booktitle={Nature communications}, year={2013} }