Spike protein VP8* of human rotavirus recognizes histo-blood group antigens in a type-specific manner.

@article{Huang2012SpikePV,
  title={Spike protein VP8* of human rotavirus recognizes histo-blood group antigens in a type-specific manner.},
  author={Pengwei Huang and Ming Xia and Ming Tan and Weiming Zhong and Chao Chun Wei and L Wang and A Leslie Morrow and Xi Jiang},
  journal={Journal of virology},
  year={2012},
  volume={86 9},
  pages={
          4833-43
        }
}
Rotaviruses (RVs), an important cause of severe diarrhea in children, have been found to recognize sialic acid as receptors for host cell attachment. While a few animal RVs (of P[1], P[2], P[3], and P[7]) are sialidase sensitive, human RVs and the majority of animal RVs are sialidase insensitive. In this study, we demonstrated that the surface spike protein VP8* of the major P genotypes of human RVs interacts with the secretor histo-blood group antigens (HBGAs). Strains of the P[4] and P[8… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 65 CITATIONS, ESTIMATED Infinity% COVERAGE

65 Citations

0510'13'15'17'19
Citations per Year
Semantic Scholar estimates that this publication has 65 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
SHOWING 1-10 OF 66 REFERENCES

Molecular epidemiology of group A rotavirus in Buenos Aires , Argentina 2004 – 2007 : reemergence of G 2 P [ 4 ] and emergence of G 9 P [ 8 ] strains

  • L Fiore, HB Greenberg, ER Mackow
  • J . Med . Virol .
  • 2010

Molecular epidemiology of group A rotavirus in Buenos Aires, Argentina

  • LE Esteban
  • J. Med. Virol
  • 2010

Similar Papers

Loading similar papers…