Spike and Slab Gene Selection for Multigroup Microarray Data

  title={Spike and Slab Gene Selection for Multigroup Microarray Data},
  author={Hemant and J Sunil},
DNA microarrays can provide insight into genetic changes that characterize different stages of a disease process. Accurate identification of these changes has significant therapeutic and diagnostic implications. Statistical analysis for multistage (multigroup) data is challenging, however. ANOVA-based extensions of two-sample Z-tests, a popular method for detecting differentially expressed genes in two groups, do not work well in multigroup settings. False detection rates are high because of… CONTINUE READING
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