Spike Protein Fusion Peptide and Feline Coronavirus Virulence

  title={Spike Protein Fusion Peptide and Feline Coronavirus Virulence},
  author={Hui-Wen Chang and Herman F. Egberink and Rebecca A. Halpin and David J. Spiro and Peter J. M. Rottier},
  booktitle={Emerging infectious diseases},
Coronaviruses are well known for their potential to change their host or tissue tropism, resulting in unpredictable new diseases and changes in pathogenicity; severe acute respiratory syndrome and feline coronaviruses, respectively, are the most recognized examples. Feline coronaviruses occur as 2 pathotypes: nonvirulent feline enteric coronaviruses (FECVs), which replicate in intestinal epithelium cells, and lethal feline infectious peritonitis viruses (FIPVs), which replicate in macrophages… CONTINUE READING
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