Spider-venom peptides: structure, pharmacology, and potential for control of insect pests.

@article{King2013SpidervenomPS,
  title={Spider-venom peptides: structure, pharmacology, and potential for control of insect pests.},
  author={Glenn F. King and Margaret C Hardy},
  journal={Annual review of entomology},
  year={2013},
  volume={58},
  pages={
          475-96
        }
}
  • G. KingM. Hardy
  • Published 14 January 2013
  • Biology
  • Annual review of entomology
Spider venoms are an incredibly rich source of disulfide-rich insecticidal peptides that have been tuned over millions of years to target a wide range of receptors and ion channels in the insect nervous system. These peptides can act individually, or as part of larger toxin cabals, to rapidly immobilize envenomated prey owing to their debilitating effects on nervous system function. Most of these peptides contain a unique arrangement of disulfide bonds that provides them with extreme resistance… 

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