Spider peptide Phα1β induces analgesic effect in a model of cancer pain.

Abstract

The marine snail peptide ziconotide (ω-conotoxin MVIIA) is used as an analgesic in cancer patients refractory to opioids, but may induce severe adverse effects. Animal venoms represent a rich source of novel drugs, so we investigated the analgesic effects and the side-effects of spider peptide Phα1β in a model of cancer pain in mice with or without… (More)
DOI: 10.1111/cas.12209

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