Spice up the hypertension diet - curcumin and piperine prevent remodeling of aorta in experimental L-NAME induced hypertension

@inproceedings{Hlavackov2011SpiceUT,
  title={Spice up the hypertension diet - curcumin and piperine prevent remodeling of aorta in experimental L-NAME induced hypertension},
  author={L{\'i}via Hlavackov{\'a} and Andrea Janegov{\'a} and Oľga Uli{\vc}n{\'a} and Pavol Janega and Andrea {\vC}ern{\'a} and Pavel Bab{\'a}l},
  booktitle={Nutrition & metabolism},
  year={2011}
}
BACKGROUND Increase of blood pressure is accompanied by functional and morphological changes in the vascular wall. The presented study explored the effects of curcuma and black pepper compounds on increased blood pressure and remodeling of aorta in the rat model of experimental NO-deficient hypertension. METHODS Wistar rats were administered for 6 weeks clear water or L-NAME (40 mg/kg/day) dissolved in water, piperine (20 mg/kg/day), curcumin (100 mg/kg/day) or their combination in corn oil… CONTINUE READING
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