Sphingosylphosphorylcholine and lysophosphatidylcholine: G protein-coupled receptors and receptor-mediated signal transduction.

@article{Xu2002SphingosylphosphorylcholineAL,
  title={Sphingosylphosphorylcholine and lysophosphatidylcholine: G protein-coupled receptors and receptor-mediated signal transduction.},
  author={Yan Xu},
  journal={Biochimica et biophysica acta},
  year={2002},
  volume={1582 1-3},
  pages={81-8}
}
  • Yan Xu
  • Published 2002 in Biochimica et biophysica acta
In recent years, certain lysophospholipids (lyso-PLs) have been recognized as important cell signaling molecules. Among them, two phosphorylcholine-containing lyso-PLs, sphingosylphosphorylcholine (SPC) and lysophosphatidylcholine (LPC), have been shown to be involved in many cellular processes and are produced under physiological and pathological conditions. Although signaling properties of SPC and LPC have been studied in a variety of cellular systems, specific cell membrane receptors for SPC… CONTINUE READING

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