Sphingosine-1-phosphate-induced smooth muscle cell migration involves the mammalian target of rapamycin.

@article{Tanski2005Sphingosine1phosphateinducedSM,
  title={Sphingosine-1-phosphate-induced smooth muscle cell migration involves the mammalian target of rapamycin.},
  author={W. Tanski and S. Nicholl and Dong Kim and A. Fegley and E. Roztocil and M. Davies},
  journal={Journal of vascular surgery},
  year={2005},
  volume={41 1},
  pages={
          91-8
        }
}
BACKGROUND Vascular smooth muscle cell (SMC) migration is an important component of the development of intimal hyperplasia. Sphingosine-1-phosphate (S-1-P) is a lipid released from activated platelets with numerous cellular effects including the stimulation of SMC migration in vitro. We examined the role of the mammalian target of rapamycin and ribosomal p70S6 kinase (p70S6K) in S-1-P-induced SMC migration . METHODS Rat arterial SMCs were cultured in vitro. Linear wound and Boyden… Expand
Mechanisms of sphingosine-1-phosphate-induced akt-dependent smooth muscle cell migration.
SRC regulates sphingosine-1-phosphate mediated smooth muscle cell migration.
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