Sphingolipid/cholesterol regulation of neurotransmitter receptor conformation and function.

Abstract

Like all other monomeric or multimeric transmembrane proteins, receptors for neurotransmitters are surrounded by a shell of lipids which form an interfacial boundary between the protein and the bulk membrane. Among these lipids, cholesterol and sphingolipids have attracted much attention because of their well-known propensity to segregate into ordered… (More)
DOI: 10.1016/j.bbamem.2009.08.016

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