Sphincter preservation with chemoradiation in anal canal carcinoma: abdominoperineal resection in selected cases?

@article{Grabenbauer1998SphincterPW,
  title={Sphincter preservation with chemoradiation in anal canal carcinoma: abdominoperineal resection in selected cases?},
  author={Gerhard G. Grabenbauer and Klaus E. Matzel and Ignaz H F Schneider and Martin Meyer and Christian Wittekind and B Matsche and Werner Hohenberger and Rolf Sauer},
  journal={Diseases of the colon and rectum},
  year={1998},
  volume={41 4},
  pages={441-50}
}
PURPOSE This study contained herein assessed long-term results, toxicity, and prognostic variables following combined modality therapy of patients with International Union Against (Cancer Classification T1-4, N0-3, M0 squamous-cell carcinoma of the anal canal. PATIENTS AND METHODS Between 1985 and 1996, 62 patients completed treatment with combined modality therapy. A median total dose of 50 Gy was given to the primary, perirectal, presacral, and inguinal nodes followed by a local boost in… CONTINUE READING

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