Spermidine synthase is prominently expressed in the striatal patch compartment and in putative interneurones of the matrix compartment.

@article{Krauss2006SpermidineSI,
  title={Spermidine synthase is prominently expressed in the striatal patch compartment and in putative interneurones of the matrix compartment.},
  author={Michael Krauss and Kristina Langnaese and K. -D. Richter and Irene Brunk and Martin Wieske and Gudrun Ahnert-Hilger and R{\"u}diger W Veh and Gregor Laube},
  journal={Journal of neurochemistry},
  year={2006},
  volume={97 1},
  pages={174-89}
}
The ubiquitous polyamines spermidine and spermine are known as modulators of glutamate receptors and inwardly rectifying potassium channels. They are synthesized by a set of specific enzymes in which spermidine synthase is the rate-limiting step catalysing the formation of the spermine precursor spermidine from putrescine. Spermidine and spermine were previously localized to astrocytes, probably reflecting storage rather than synthesis in these cells. In order to identify the cellular origin of… CONTINUE READING

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