Spermidine regulates Vibrio cholerae biofilm formation via transport and signaling pathways.

@article{McGinnis2009SpermidineRV,
  title={Spermidine regulates Vibrio cholerae biofilm formation via transport and signaling pathways.},
  author={Marcus W. McGinnis and Zachary M. Parker and Nicholas Emmanuel Walter and Alex C. Rutkovsky and Claudia Cartaya-Marin and Ece Karatan},
  journal={FEMS microbiology letters},
  year={2009},
  volume={299 2},
  pages={166-74}
}
Vibrio cholerae, the causative agent of the devastating diarrheal disease cholera, can form biofilms on diverse biotic and abiotic surfaces. Biofilm formation is important for the survival of this organism both in its natural environment and in the human host. Development of V. cholerae biofilms are regulated by complex regulatory networks that respond to environmental signals. One of these signals, norspermidine, is a polyamine that enhances biofilm formation via the NspS/MbaA signaling system… CONTINUE READING