Spermatozoa recruit prostasomes in response to capacitation induction.

  title={Spermatozoa recruit prostasomes in response to capacitation induction.},
  author={Marian Aalberts and Edita Sostaric and Richard W. Wubbolts and Marca W M Wauben and Esther N M Nolte-'t Hoen and Bart M Gadella and Tom A E Stout and Willem Stoorvogel},
  journal={Biochimica et biophysica acta},
  volume={1834 11},
Seminal plasma contains various types of extracellular vesicles, including 'prostasomes'. Prostasomes are small vesicles secreted by prostatic epithelial cells that can be recruited by and fuse with sperm cells in response of progesterone that is released by oocyte surrounding cumulus cells. This delivers Ca(2+) signaling tools that allow the sperm cell to gain hypermotility and undergo the acrosome reaction. Conditions for binding of prostasomes to sperm cells are however unclear. We found… CONTINUE READING


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