Spermatogonial stem cells, infertility and testicular cancer

  title={Spermatogonial stem cells, infertility and testicular cancer},
  author={Shree Ram Singh and Ozanna Burnicka-Turek and Chhavi Chauhan and Steven X. Hou},
  booktitle={Journal of cellular and molecular medicine},
The spermatogonial stem cells (SSCs) are responsible for the transmission of genetic information from an individual to the next generation. SSCs play critical roles in understanding the basic reproductive biology of gametes and treatments of human infertility. SSCs not only maintain normal spermatogenesis, but also sustain fertility by critically balancing both SSC self-renewal and differentiation. This self-renewal and differentiation in turn is tightly regulated by a combination of intrinsic… CONTINUE READING
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