Spermatogenesis Associated Retrogenes Are Expressed in the Human Ovary and Ovarian Cancers

  title={Spermatogenesis Associated Retrogenes Are Expressed in the Human Ovary and Ovarian Cancers},
  author={J. Rohozinski and M. Anderson and R. Broaddus and C. Edwards and C. Bishop},
  journal={PLoS ONE},
  • J. Rohozinski, M. Anderson, +2 authors C. Bishop
  • Published 2009
  • Medicine, Biology
  • PLoS ONE
  • Background Ovarian cancer is the second most prevalent gynecologic cancer in women. However, it is by far the most lethal. This is generally attributed to the absence of easily detectable markers specific to ovarian cancers that can be used for early diagnosis and specific therapeutic targets. Methodology/Principal Findings Using end point PCR we have found that a family of retrogenes, previously thought to be expressed only in the male testis during spermatogenesis in man, are also expressed… CONTINUE READING
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