Sperm nuclei analysis of 1/29 Robertsonian translocation carrier bulls using fluorescence in situ hybridization.

@article{BonnetGarnier2006SpermNA,
  title={Sperm nuclei analysis of 1/29 Robertsonian translocation carrier bulls using fluorescence in situ hybridization.},
  author={Am{\'e}lie Bonnet-Garnier and Alain Pinton and H. M. Berland and B Khireddine and Andr{\'e} Eggen and Martine Yerle and Roland Darr{\'e} and Alain Ducos},
  journal={Cytogenetic and genome research},
  year={2006},
  volume={112 3-4},
  pages={241-7}
}
In 1964, Gustavsson and Rockborn first described the 1/29 Robertsonian translocation in cattle. Since then, several studies have demonstrated the negative effect of this particular chromosomal rearrangement on the fertility of carrier animals. During the last decade, meiotic segregation patterns have been studied on human males carrying balanced translocations using FISH on decondensed sperm nuclei. In this work, we have applied the 'Sperm-FISH' technique to determine the chromosomal content of… CONTINUE READING