Sperm mitochondrial DNA depletion in men with asthenospermia.

  title={Sperm mitochondrial DNA depletion in men with asthenospermia.},
  author={Shu-Huei Kao and Hsiang-Tai Chao and Hwan-wun Liu and T J Liao and Yau-Huei Wei},
  journal={Fertility and sterility},
  volume={82 1},
OBJECTIVE To determine the content of sperm mitochondrial DNA (mtDNA) in patients with asthenospermia or with poor sperm motility. DESIGN Analysis of the content of mtDNA as the ratio between the amount of mtDNA and nuclear DNA by using a new concurrent polymerase chain reaction. SETTING University hospital infertility center. PATIENT(S) Eighty-six men who sought infertility therapy. INTERVENTION(S) Moving characteristics of sperm were examined with a computer-assisted semen analyzer… CONTINUE READING
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