Sperm ecto-protein kinase and its protein substrate: novel regulators of membrane fusion during acrosome reaction.

@article{Maiti2009SpermEK,
  title={Sperm ecto-protein kinase and its protein substrate: novel regulators of membrane fusion during acrosome reaction.},
  author={Arunima Maiti and Debjani Nath and Sandhya R Dungdung and Gopal Chandra Majumder},
  journal={Journal of cellular physiology},
  year={2009},
  volume={220 2},
  pages={
          394-400
        }
}
Previously we have purified and characterized a unique plasma membrane-specific cyclic AMP-independent ecto-protein kinase (ecto-CIK) as well as its ecto-phosphoprotein substrate (MPS) using caprine sperm model. This study reports for the first time the role of the sperm external surface protein phosphorylation system on sperm acrosome reaction, which is essential for fertilization. Calcium ionophore A23187 has been used to trigger the sperm acrosome reaction in vitro. Treatment of sperm cells… CONTINUE READING

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