Sperm capacitation and the acrosome reaction.

  title={Sperm capacitation and the acrosome reaction.},
  author={Lynn R Fraser},
  journal={Human reproduction},
  volume={13 Suppl 1},
To achieve successful fertilization under normal circumstances in vivo, mammalian spermatozoa must first undergo capacitation and then the acrosome reaction, an exocytotic event that allows cells to penetrate the zona pellucida and fuse with the oocyte plasma membrane. These complex events permit spermatozoa to achieve fertilizing ability at the right time in the right place, important considerations since relatively few sperm cells actually reach the site of fertilization in vivo. Several… CONTINUE READING


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