Sperm-associated oocyte-activating factor is released from the spermatozoon within 30 minutes after injection as a result of the sperm-oocyte interaction.

@article{Dozortsev1997SpermassociatedOF,
  title={Sperm-associated oocyte-activating factor is released from the spermatozoon within 30 minutes after injection as a result of the sperm-oocyte interaction.},
  author={Dmitri I Dozortsev and Chen Zi Qian and Alexandre N. Ermilov and Andre{\"i} Rybouchkin and P D de Sutter and Marc A Dhont},
  journal={Human reproduction},
  year={1997},
  volume={12 12},
  pages={2792-6}
}
We have previously shown that sperm plasma membrane damage makes the sperm plasma membrane permeable and the sperm nucleus accessible for low molecular weight molecules such as eosin and dithiothreitol. In the present study, we investigated whether this damage is associated with a passive release of the sperm-associated oocyte activating factor (SAOAF) from the spermatozoon and, if so, its time sequence. In a first study, human oocytes remaining unfertilized after conventional in-vitro… CONTINUE READING