Sperm-associated antigen 9 is a novel biomarker for colorectal cancer and is involved in tumor growth and tumorigenicity.

@article{Kanojia2011SpermassociatedA9,
  title={Sperm-associated antigen 9 is a novel biomarker for colorectal cancer and is involved in tumor growth and tumorigenicity.},
  author={Deepika Kanojia and Manoj K. Garg and Samir K Gupta and Anju Gupta and Anil Suri},
  journal={The American journal of pathology},
  year={2011},
  volume={178 3},
  pages={1009-20}
}
Colorectal cancer (CRC) is the second most common tumor in developed countries. The present study was undertaken to determine the expression of the sperm-associated antigen 9 gene (SPAG9) as a possible biomarker in CRC, to investigate its correlation with humoral immune response and different stages and grades in CRC patients, and to explore its possible role in colon tumorigenesis in vitro and in an in vivo mouse model. SPAG9 expression was determined by RT-PCR, in situ RNA hybridization, and… CONTINUE READING