Sperm DNA fragmentation and oxidation are independent of malondialdheyde

  title={Sperm DNA fragmentation and oxidation are independent of malondialdheyde},
  author={Nassira Zribi and Nozha Feki Chakroun and Henda Elleuch and Fatma Ben Abdallah and Afifa Sellami Ben Hamida and Jalel Gargouri and Faiza Fakhfakh and Leila Keskes},
  booktitle={Reproductive biology and endocrinology : RB&E},
BACKGROUND There is clinical evidence to show that sperm DNA damage could be a marker of sperm quality and extensive data exist on the relationship between DNA damage and male fertility status. Detecting such damage in sperm could provide new elements besides semen parameters in diagnosing male infertility. We aimed to assess sperm DNA fragmentation and oxidation and to study the association between these two markers, routine semen parameters and malondialdehyde formation. METHODS Semen… CONTINUE READING


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Analysis of the relationships between oxidative stress, DNA damage and sperm vitality in a patient population: development of diagnostic criteria

  • RJ Aitken, GN De Iuliis, JM Finnie, A Hedges, RI McLachlan
  • Hum Reprod
  • 2010
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