Sperm DNA damage: clinical significance in the era of assisted reproduction.

@article{Zini2006SpermDD,
  title={Sperm DNA damage: clinical significance in the era of assisted reproduction.},
  author={Armand Zini and Jamie L Libman},
  journal={CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne},
  year={2006},
  volume={175 5},
  pages={
          495-500
        }
}
Evidence suggests that damage to human sperm DNA might adversely affect reproductive outcomes and that the spermatozoa of infertile men possess substantially more sperm DNA damage than do the spermatozoa of fertile men. This is particularly relevant in an era where advanced forms of assisted reproductive technologies are commonly used (technologies that often bypass the barriers to natural selection), because there is some uncertainty regarding the safety of using DNA-damaged spermatozoa. In… CONTINUE READING

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