Spectrum of saccade system function in Alzheimer disease.

  title={Spectrum of saccade system function in Alzheimer disease.},
  author={Ruxsana Shafiq-Antonacci and Paul Maruff and Colin J. Masters and Jon Currie},
  journal={Archives of neurology},
  volume={60 9},
BACKGROUND In Alzheimer disease (AD), tests of "first-order capabilities," such as reaction time or motor ability, might measure central nervous system integrity or disability more reliably than those of abstract, conceptual, or cognitive behavior. Saccade system impairments are present in AD, but their sensitivity or specificity remains unevaluated. OBJECTIVES To determine sensitivity and specificity of saccade measures for AD, precise impairments in AD, and the relationship between dementia… CONTINUE READING
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