Spectrum of gait impairments in presymptomatic and symptomatic Huntington's disease.

@article{Rao2008SpectrumOG,
  title={Spectrum of gait impairments in presymptomatic and symptomatic Huntington's disease.},
  author={A. K. Prasada Rao and Lisa M. Muratori and Elan Daniel Louis and Carol Brown Moskowitz and Karen S. Marder},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  year={2008},
  volume={23 8},
  pages={1100-7}
}
The purpose of this study was to quantify gait impairments in presymptomatic and symptomatic Huntington's disease (HD) subjects, and examine sensitivity of gait measures. Our sample (n = 65) included presymptomatic mutation carriers (PMC) (n = 15), symptomatic HD subjects (SHD) (n = 30) and healthy controls (n = 20). Participants were requested to walk at their preferred speed on a computerized walkway that recorded spatiotemporal variables. We administered the Unified HD Rating Scale (UHDRS… CONTINUE READING

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