Spectrum of disease in familial focal and segmental glomerulosclerosis.

  title={Spectrum of disease in familial focal and segmental glomerulosclerosis.},
  author={Peter J Conlon and K. Lynn and Michelle P. Winn and Leigh Quarles and Marylou Bembe and Margaret A. Pericak-Vance and Marcy C. Speer and David N. Howell},
  journal={Kidney international},
  volume={56 5},
BACKGROUND Focal segmental glomerulosclerosis (FSGS) is the underlying pathologic entity in 5% of adults and 20% of children with end-stage renal disease (ESRD). FSGS is generally considered to be sporadic in origin. METHODS Recently, we identified 60 families involving 190 individuals with familial FSGS, providing evidence for a subset of families in which a genetic form is segregating. Each family had at least one member with renal biopsy-confirmed FSGS and at least one other member with… CONTINUE READING


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Annual Data Report

  • A Valeri, L Barisoni, GB Appel, R Seigle, V D’Agati
  • United States Renal Data System:
  • 1995
1 Excerpt

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