Spectrum of Epstein-Barr virus-related diseases: a pictorial review

@article{Maeda2008SpectrumOE,
  title={Spectrum of Epstein-Barr virus-related diseases: a pictorial review},
  author={Eriko Maeda and Masaaki Akahane and Shigeru Kiryu and Nobuyuki Kato and Takeharu Yoshikawa and Naoto Hayashi and Shigeki Aoki and Manabu Minami and Hiroshi Uozaki and Masashi Fukayama and Kuni Ohtomo},
  journal={Japanese Journal of Radiology},
  year={2008},
  volume={27},
  pages={4-19}
}
Epstein-Barr virus (EBV) prevails among more than 90% of the adult population worldwide. Most primary infections occur during young childhood and cause no or only nonspecific symptoms; then the virus becomes latent and resides in lymphocytes in the peripheral blood. Inactive latent EBV usually causes no serious consequences, but once it becomes active it can cause a wide spectrum of malignancies: epithelial tumors such as nasopharyngeal and gastric carcinomas; mesenchymal tumors such as… 
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A 59-year-old woman who underwent an excisional biopsy for a left axillary mass under suspicion of malignant lymphoma is reported a rare case of EBV associated FL of lymph node with its review of literature.

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LPD seen in an autopsy case of aplastic anemia after immunosuppressive therapy using anti-thymocyte globulin (ATG) twice is reported, and EBV-infected highly proliferative lymphoplasmacytic cells showed polyclonality.

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EBV infection may be a factor involved in the high incidence of pediatric lymphoma; this study suggests a positive influence of EBV infection in pediatric lymphomas.

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Findings suggest that the EBV-positivity rate in lymphomas is related to their histological types and locations.
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