Spectroscopy of human plasma for diagnosis of idiopathic Parkinson's disease.

  title={Spectroscopy of human plasma for diagnosis of idiopathic Parkinson's disease.},
  author={Hyman M. Schipper and Chun Shing Kwok and Scott M Rosendahl and Dirk Bandilla and Olivier Charles Maes and Calvin Melmed and Daniel Rabinovitch and David W. Burns},
  journal={Biomarkers in medicine},
  volume={2 3},
BACKGROUND No established chemical biomarkers of idiopathic Parkinson's disease (PD) currently exist. Augmented oxidative stress (OS) has been implicated in both neural and peripheral PD tissues. METHODS In this study, Raman scattering and near-infrared spectroscopy were used to detect and quantify oxidative substrate modifications in blood plasma samples from PD and normal elderly control (NEC) subjects. RESULTS Hypothesis-driven preselection of OS-sensitive bandwidths distinguished PD… CONTINUE READING

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