Spectroscopic study of conformational changes accompanying self-assembly of HCV core protein.

@article{RodrguezCasado2007SpectroscopicSO,
  title={Spectroscopic study of conformational changes accompanying self-assembly of HCV core protein.},
  author={Arantxa Rodr{\'i}guez-Casado and M. Gutierrez Molina and Pedro Carmona},
  journal={Proteins},
  year={2007},
  volume={66 1},
  pages={110-7}
}
Electron microscopy and infrared and Raman spectroscopy have been used here to study the morphology, size distribution, secondary and tertiary structures of protein particles assembled from a truncated hepatitis C virus (HCV) core protein covering the first 120 aa. Particles of pure protein, having similar morphology and size distribution of those of nucleocapsids found in sera from HCV-infected patients, have been visualized for the first time. The secondary structure of these protein… CONTINUE READING