Spectroscopic studies on the in vitro antioxidant capacity of isopentyl ferulate.

@article{Machado2015SpectroscopicSO,
  title={Spectroscopic studies on the in vitro antioxidant capacity of isopentyl ferulate.},
  author={K. C. Machado and G. L. Oliveira and {\'E}. B. V. de Sousa and I. Costa and D. P. de Sousa and P. Satyal and R. M. de Freitas},
  journal={Chemico-biological interactions},
  year={2015},
  volume={225},
  pages={
          47-53
        }
}
Essential oils have played a prominent role in research on natural products, due to the high level of bioactive constituents, which include those derived from phenylpropanoids or terpenoids. This study aimed to evaluate the antioxidant capacity of isopentyl ferulate (IF) employing in vitro experimental models for elimination of the 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS+), hydroxyl (OH) and nitric oxide (NO), as well as its capacity to… Expand
In vitro antioxidant properties of the biflavonoid agathisflavone
TLDR
The antioxidant capacity, reducing potential and inhibition of lipid peroxidation showed by agathisflavone were comparable to that of trolox, which suggests considering this biflavonoid for the use in the prevention and/or treatment of diseases precipitated by oxidative stress. Expand
In vitro and in vivo toxicological evaluations of methyl ferulate, methyl p-coumarate, and pulegone 1,2-epoxide
TLDR
The present studies suggest that methyl ferulate, methyl p-coumarate, and pulegone 1,2-epoxide are non-toxic/non-irritant and might be used for medicinal purposes. Expand
Evaluation of the Antioxidant Activity of Cis/Trans-N-Phenyl-1,4,4a,5,8,8a-Hexahydro-3,1-Benzoxazin-2-Imines
TLDR
The evaluation of the in vitro and ex vivo antioxidant activity of two cyclohexene-fused oxazines is discussed and suggests that both unsaturated 1,3-oxazines are auspicious sources of biologically active compounds with good antioxidant properties. Expand
Evaluation of antioxidant potencial of novel CaAl and NiAl layered double hydroxides loaded with olanzapine
TLDR
The results revealed that the use of LDHs as a functional excipient may be promising in the pharmaceutical industry for bipolar disorder and schizophrenia therapy. Expand
Investigations of cytotoxic and mutagenic effects of some synthetic compounds of natural origin
Investigations of cytotoxic and mutagenic effects of limonene 1, 2-epoxide (LE), hydroxycitronellal (HC), thymyl acetate (ThA), terpinyl acetate (TrA), and isopulegone (IS) were carried out. TheExpand
Effects of isopentyl ferulate on oxidative stress biomarkers and a possible GABAergic anxiolytic-like trait in Swiss mice.
TLDR
IF exhibited an anxiety-like effect in mice along with a potent antioxidant capacity, and it is suppose it may have neuroprotective effects possibly via GABAergic transmission pathway. Expand
Beneficial role of vanillin, a polyphenolic flavoring agent, on maneb-induced oxidative stress, DNA damage, and liver histological changes in Swiss albino mice
TLDR
Vanillin significantly reduced the elevated hepatic levels of malondialdehyde, hydrogen peroxide, and advanced oxidation protein product and attenuated DNA fragmentation induced by maneb and concluded that vanillin might be beneficial against maneb-induced hepatic damage in mice. Expand
Identification and characterization of potential antioxidant components in Isodon amethystoides (Benth.) Hara tea leaves by UPLC-LTQ-Orbitrap-MS.
  • Hong Duan, Guo-cheng Wang, +6 authors Ke-Feng Zhai
  • Medicine
  • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 2020
TLDR
The results provide experimental basis for extraction and separation of chemical constituents of IA which are antioxidant in nature and profound correlation was observed between diterpenoid compounds content and flavonoids activity. Expand
Overview of the Role of Vanillin on Redox Status and Cancer Development
TLDR
The role of vanillin on redox status and its potential contribution to the prevention and the treatment of cancer are discussed. Expand
Anticonvulsant and behavioral effects observed in mice following treatment with an ester derivative of ferulic acid: Isopentyl ferulate.
TLDR
The results showed that the IF does not induce significant changes in locomotor activity and motor coordination when compared with the control group, unlike the results presented by diazepam, demonstrating a new pharmacological knowledge of IF with potential application against epileptic seizures. Expand
...
1
2
...

References

SHOWING 1-10 OF 53 REFERENCES
Antioxidant and prooxidant nature of hydroxycinnamic acid derivatives ferulic and caffeic acids.
  • D. Maurya, T. Devasagayam
  • Chemistry, Medicine
  • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 2010
TLDR
Ferulic and caffeic acids have concentration-dependent antioxidant effects in terms of inhibition of lipid peroxidation and reactive oxygen species-scavenging after 2,2'-azobis-amidinopropane dihydrochloride-induced damage in mouse liver microsomes and splenic lymphocytes respectively. Expand
Lipase-catalysed synthesis of esters of ferulic acid with natural compounds and evaluation of their antioxidant properties
Abstract Lipases from Candida antarctica (Novozyme 435 ® ), Candida rugosa , Chromobacterium viscosum and Pseudomonas sp. were used to perform transesterifications of vinyl ferulate withExpand
Conformational analysis: a tool for the elucidation of the antioxidant properties of ferulic acid derivatives in membrane models.
TLDR
The results emphasize the need of analytical studies addressed to the knowledge of the conformational parameters in combination with conventional antioxidant testings for understanding the antioxidant behaviour of a molecule in a biological membrane/system. Expand
Evaluation of antioxidant capacity of the aqueous extract of Cynara scolymus L. (Asteraceae) in vitro and in Saccharomyces cerevisiae
The present study evaluated the antioxidant capacity of the aqueous extract of the leaves of Cynara scolymus on Saccharomyces cerevisiae strains, proficient and deficient in antioxidant defenses, andExpand
Alkyl esters of hydroxycinnamic acids with improved antioxidant activity and lipophilicity protect PC12 cells against oxidative stress.
TLDR
Alkyl esterification of some HCAs augments their antioxidant properties as well as their lipophilicity and as a consequence, improves their cell protective activity against oxidative stress. Expand
Antioxidant activity applying an improved ABTS radical cation decolorization assay.
A method for the screening of antioxidant activity is reported as a decolorization assay applicable to both lipophilic and hydrophilic antioxidants, including flavonoids, hydroxycinnamates,Expand
Evaluation of antioxidant activity of Brazilian plants.
TLDR
Four extracts exhibited a DPPH radical scavenging activity higher than that obtained from Ginkgo biloba, a reference plant with well documented antioxidant activity, suggesting that these plant extracts could be considered as potential sources of antioxidants. Expand
Evaluation of nitric oxide scavenging activity, In Vitro and Ex Vivo, of selected medicinal plants traditionally used in inflammatory diseases
TLDR
Four traditional medicinal plants selected for a study on the inhibition of nitric oxide (NO•), a key mediator in the phenomenon of inflammation, showed marked inhibition ex vivo at a dose of 80 µg/mL without appreciable cytotoxic effect on the cultured macrophages. Expand
Assessment of free radicals scavenging activity of seven natural pigments and protective effects in AAPH-challenged chicken erythrocytes.
TLDR
It was found that both curcumin and cyanidin-3-rutinoside significantly attenuated apoptosis and hemolysis, decreased MDA content, and increased T-SOD activity in a time- and dose- dependent manner. Expand
Polyphenol tannic acid inhibits hydroxyl radical formation from Fenton reaction by complexing ferrous ions.
TLDR
The results indicate that the antioxidant activity of TA is mainly due to iron chelation rather than *OH scavenging, and it is proposed that when Fe(II) is complexed to TA, it is unable to participate in Fenton reactions and mediate *OH formation. Expand
...
1
2
3
4
5
...