Spectroscopic increase in choline signal is a nonspecific marker for differentiation of infective/inflammatory from neoplastic lesions of the brain.

@article{Venkatesh2001SpectroscopicII,
  title={Spectroscopic increase in choline signal is a nonspecific marker for differentiation of infective/inflammatory from neoplastic lesions of the brain.},
  author={Sudhakar K. Venkatesh and Rakesh Kumar Gupta and Lily Pal and Nuzhat Husain and Mazhar Husain},
  journal={Journal of magnetic resonance imaging : JMRI},
  year={2001},
  volume={14 1},
  pages={8-15}
}
We report in vivo proton magnetic resonance (MR) spectroscopic findings in three benign infective/inflammatory lesions (one case each of tuberculoma, fungal granuloma, and xanthogranuloma), which showed high choline along with the presence of lipid/lactate, a feature characteristically described in neoplastic lesions. Histopathology of the lesions showed inflammatory cellular infiltrates with areas of necrosis/caseation. The spectroscopic-visible increased choline resonance in these lesions is… CONTINUE READING

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