Spectrophotometry-based detection of carbapenemase producers among Enterobacteriaceae.

@article{Bernabeu2012SpectrophotometrybasedDO,
  title={Spectrophotometry-based detection of carbapenemase producers among Enterobacteriaceae.},
  author={Sandrine Bernabeu and Laurent Poirel and Patrice L. Nordmann},
  journal={Diagnostic microbiology and infectious disease},
  year={2012},
  volume={74 1},
  pages={
          88-90
        }
}
  • Sandrine Bernabeu, Laurent Poirel, Patrice L. Nordmann
  • Published in
    Diagnostic microbiology and…
    2012
  • Biology, Medicine
  • Carbapenem-hydrolyzing ß-lactamases are the most powerful ß-lactamases being able to hydrolyse almost all ß-lactams. They are mostly of the KPC, VIM, IMP, NDM, and OXA-48 type. A spectrophotometry technique based on analysis of the imipenem hydrolysis has been developed that differentiated carbapenemase- from noncarbapenemase producers. This inexpensive technique adapted to screening of carbapenemase producers may be implemented in any reference laboratory worldwide. 

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