Spectrophotometric determination of carminic acid in human plasma and fruit juices by second order calibration of the absorbance spectra-pH data matrices coupled with standard addition method.

@article{Samari2010SpectrophotometricDO,
  title={Spectrophotometric determination of carminic acid in human plasma and fruit juices by second order calibration of the absorbance spectra-pH data matrices coupled with standard addition method.},
  author={Fayezeh Samari and Bahram Hemmateenejad and Mojtaba Shamsipur},
  journal={Analytica chimica acta},
  year={2010},
  volume={667 1-2},
  pages={49-56}
}
A simple analytical method based on the second-order calibration of the pH gradient spectrophotometric data was developed for assay of carminic acid (CA) in human plasma and orange juice over the concentration range of 1.5-14.0microM. The multi-way data analysis method was coupled with standard addition to encounter the significant effects of plasma and juices matrices on the acid-base behavior and UV-vis. absorbance spectra of CA. Thus, the standard addition three-way calibration data of… CONTINUE READING