Spectrophotometric and spectrofluorimetric methods for determination of Racecadotril.

  title={Spectrophotometric and spectrofluorimetric methods for determination of Racecadotril.},
  author={Nouruddin Wageih Ali and Mohammed Refaat Elghobashy and Mohammed Gamal Mahmoud and Mohammed Abdelkawy Mohammed},
  journal={Pakistan journal of pharmaceutical sciences},
  volume={24 1},
Two accurate and sensitive spectrophotometric and spectrofluorimetric methods were developed for determination of Racecadotril. In the first method reduction of Fe3+ into Fe2+ in presence of o-phenanthroline by Racecadotril to form a stable orange-red ferroin chelate [Fe-(Phen)3]2+ was the basis for its determination. The absorbance at 510 nm was measured and linear correlation was obtained in the concentration range of 2.5-25 µg mL(-1). In the second method the native fluorescence of… CONTINUE READING

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