Spectrophotometric and HPTLC-densitometric determination of lisinopril and hydrochlorothiazide in binary mixtures.

@article{ElGindy2001SpectrophotometricAH,
  title={Spectrophotometric and HPTLC-densitometric determination of lisinopril and hydrochlorothiazide in binary mixtures.},
  author={Alaa M L El-Gindy and Ahmed Ashour and Laila E Abdel-Fattah and Marwan M Shabana},
  journal={Journal of pharmaceutical and biomedical analysis},
  year={2001},
  volume={25 5-6},
  pages={923-31}
}
Different spectrophotometric and HPTLC-densitometric methods are presented for the simultaneous determination of lisinopril and hydrochlorothiazide in pharmaceutical tablets. The spectrophotometric methods include third derivative (3D) ultraviolet spectrophotometry with zero crossing measurement at 217.4 and 233.4 nm, second derivative of the ratio spectra with measurement at 214.3 and 228.0 nm; both classical least squares and principal component regression were applied to the UV absorption… CONTINUE READING
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