Spectrofluorimetric determination of gemifloxacin mesylate and linezolid in pharmaceutical formulations: Application of quinone-based fluorophores and enhanced native fluorescence

@inproceedings{Moussa2014SpectrofluorimetricDO,
  title={Spectrofluorimetric determination of gemifloxacin mesylate and linezolid in pharmaceutical formulations: Application of quinone-based fluorophores and enhanced native fluorescence},
  author={B. Moussa and M. A. Mahrouse and M. Hassan and Michael Gamal Fawzy},
  booktitle={Acta pharmaceutica},
  year={2014}
}
  • B. Moussa, M. A. Mahrouse, +1 author Michael Gamal Fawzy
  • Published in Acta pharmaceutica 2014
  • Chemistry, Medicine
  • Abstract Quinone-based fluorophores and enhanced native fluorescence techniques were applied for a fast quantitative analysis of gemifloxacin mesylate (GEM) and linezolid (LIN) in pharmaceutical formulations. For this purpose, three sensitive, accurate and precise spectrofluorimetric methods were developed. GEM, as an n-electron donor, reacts with 7,7,8,8-tetracyanoquinodimethane (method A) and 2,5-dichloro-3,6-dihydroxy-p-benzoquinone (method B) as п-electron acceptors, forming charge transfer… CONTINUE READING
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