Spectral triangulation molecular contrast optical coherence tomography with indocyanine green as the contrast agent.

@article{Yang2004SpectralTM,
  title={Spectral triangulation molecular contrast optical coherence tomography with indocyanine green as the contrast agent.},
  author={Changhuei Yang and Laura E L McGuckin and J. D. Simon and Michael A. Choma and Brian E. Applegate and Joseph A. Izatt},
  journal={Optics letters},
  year={2004},
  volume={29 17},
  pages={2016-8}
}
We report a new molecular contrast optical coherence tomography (MCOCT) implementation that profiles the contrast agent distribution in a sample by measuring the agent's spectral differential absorption. The method, spectra triangulation MCOCT, can effectively suppress contributions from spectrally dependent scatterings from the sample without a priori knowledge of the scattering properties. We demonstrate molecular imaging with this new MCOCT modality by mapping the distribution of indocyanine… CONTINUE READING

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